Nature is the world's most highly cited interdisciplinary science journal. Toolbox, which is hosted in the News & Comment section of Nature's website, reports on the software and websites that make research easier for investigators engaged in science and technology subjects, from molecular biology to astrophysics, and beyond. Readers will find articles here about software, such as Excel, ChemDraw, and MATLAB, and the programming languages that are used to build that software, including Python, R, and SQL. Readers may like to start with the September 4, 2014 editorial describing the site, and from there browse articles about computing skills "Boot Camps," learning to program with R, and other topics.