Getting students into the laboratory early in their college careers is quite important, and science educators can use this helpful resource to do just that. Created by Professor Sarah Elgin at Washington University, this lab exercise and guide introduces students to the molecular biology techniques used to clone a gene. Over the course of this activity, students sequence a small fragment of the yeast genome and then determine what genes, control elements, or repetitive sequences this fragment contains. The file contains pages for the instructor detailing how to conduct the activity and a selection of pages for students designed to test and interrogate what they have learned through this process of scientific inquiry.