As part of the National Institutes of Health (NIH), the National Human Genome Research Institute's (NHGRI) Division of Intramural Research (DIR) conducts research regarding the genetic component of human disease. The Homeodomain Resource presents "an annotated collection of non-redundant protein sequences, three-dimensional structures, and genomic information for the homeodomain protein family." In addition to providing compilations of data from the literature, this Web site features a homeodomain database that can be searched by a number of criteria, including gene sequence, protein name, organism, and gene symbol.