New from the Weizmann Institute of Science (WIS) Genome Center, ExPASy Proteomics Tools is a comprehensive collection of protein-related databases and services for researchers. Listed and briefly described at the site are a wide variety of research tools allowing users to: identify a protein by its amino acid composition; translate a nucleotide sequence to a protein sequence; conduct similarity, pattern and profile searches; determine physico-chemical parameters of a protein sequence; color an amino acid sequence; predict protein secondary structure; analyze and superimpose protein 3D structures (tertiary structure); predict transmembrane regions in prokaryotes; and align protein sequences -- to name a few.