The University at Buffalo's National Center for Case Study Teaching in Science is a well-known resource in the promotion, development, and dissemination of case teaching methods and practices, offering users access to an award-winning collection of peer-reviewed case studies. This case study, written by biologist Karen M. Aguirre, introduces students to the 19th century physician E.L. Trudeau and his quest to mitigate the deadly outcomes of tuberculosis. The study itself is available as a downloadable PDF and is divided into two parts. Part one presents an autobiography of Dr. Trudeau, including what led to his prescriptions of nature, isolation, diet, and exercise for the treatment of TB. This section culminates in nine provocative questions, including "Do Dr. Trudeau's results support the theory of the germ theory of infection?" The second section of the case study then examines the social context of tuberculosis treatment throughout history and features an excellent line graph depicting the increasing efficacy of treatments. Teaching Notes and an Answer Key are also available here. For educators teaching the history of epidemiology, this case study will provide rich material.