Materials from this intriguingly titled Massachusetts Institute of Technology (MIT) course about biological systems are freely available to students, educators, and others through MIT's OpenCourseWare. The course covers a variety of topics including "conduction, diffusion, convection in electrolytes; fields in heterogeneous media; electrical double layers; Maxwell stress tensor and electrical forces in physiological systems; and fluid and sold continua: equations of motion useful for porous, hydrated biological tissues. Case studies considered include membrane transport; electrode interfaces; electrical, mechanical, and chemical transduction in tissues; electrophoretic and electroosmotic flows; diffusion/reaction; and ECG." This OpenCourseWare website provides downloadable notes for 25 lectures; seven downloadable assignments with solutions; and a pdf version of the final exam. The site links to an open, online discussion group for the course as well.