04/17/2024
Research Article
Role of chromatin factor CFDP1 in mitotic spindle formation
CFDP1 is a chromatin factor that has been shown to regulate cell proliferation and maintain higher-order chromatin structure, but its mechanistic role in mitotic spindle assembly is unclear. Gokul Gopinathan, Qian Xu, Xianghong Luan and Thomas Diekwisch show that CFDP1 is essential for the structural stability of centromeric heterochromatin, which in turn influences microtubule nucleation during mitotic spindle formation.
Image credit: pbio.3002574
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